Abstract: Cyantraniliprole (DPX-HGW86, DuPont™ Cyazypyr™ 1) a new DuPont anthranilicdiamide insecticide is being developed for insect pest control for many in- and out-door vegetableand top fruit crops. DuPont™ Cyazypyr™ based formulations may be applied via sprayapplication twice at up to 150g cyantraniliprole/ha per application (Cyantraniliprole 100g/l ODand Cyantraniliprole 100g/l SE) or via drip irrigation twice at up to 75g cyantraniliprole/ha perapplication (Cyantraniliprole 200g/l SC) in outdoor crops, and up to four times in some indoorcrops. The regulatory non-target arthropod data package comprises worst-case Tier 1 laboratorystudies, extended Tier 2 laboratory studies, semi-field and field studies with the straightcyantraniliprole formulations or applied with the adjuvant, Codacide®, and includes the followingtest species: Typhlodromus pyri (and other mite species), iAphidius rhopalosiphi, Chrysoperlacarnea, Coccinella septempunctata, Pardosa spp. and Aleochara bilineata. For some beneficialspecies tested, e.g. Typhlodromus pyri and Pardosa spp. no negative effects were found evenunder worst-case Tier 1 or Tier 2 laboratory conditions up to the intended maximum use rates ofcyantraniliprole, while Aphidius rhopalosiphi was identified as the most sensitive species tested.DuPont™ Cyazypyr™ based formulations, Cyantraniliprole 100g/l OD, Cyantraniliprole 100g/lSE and Cyantraniliprole 200g/l SC will be valuable tools in integrated pest management (IPM)programs and are unlikely to have unacceptable effects on in-field and off-field populations ofnon-target arthropods.1 DuPont™ Cyazypyr™, Rynaxypyr®, Coragen® and Altacor® are trademarks or registered trademarks of DuPont or its affiliates. Copyright © 2004 E.I. du Pont de Nemours and Company or its affiliates. All rights reserved.